Corona Links, 20th March, 2020

Christopher Balding runs the numbers, and says that the virus is spreading faster than we think, but is not as deadly as we feared.

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Scott Alexander analyzes (and I mean analyzes!) masks.

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Via MR, an obituary for Maurice Hilleman from the Economist in 2005:

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Mr Hilleman’s greatest contribution to a healthy world may have been his work on the safe mass production of vaccines that can be stored ready for use against the pandemics that since antiquity have regularly swept across continents, such as the 1918 flu outbreak that killed more than 20m people. In 1957, when flu swept through Hong Kong, Mr Hilleman identified the virus as a new form to which people had no natural immunity and passed on his findings to vaccine-makers. When the virus reached the United States a few months later 40m doses of vaccine were ready to limit its damage. Mr Hilleman established that the flu virus is constantly mutating, making it difficult to provide a reliable vaccine. Developing a vaccine can be complex. His fellow-workers saw him as an artist as much as a scientist, bringing to his discipline an instinctive feeling of what would work. Following his guidelines, many nations are making large quantities of what they believe will be useful vaccines in the hope of defeating a possible pandemic of bird flu, should the virus spread from Asia.

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An Ask Me Anything (AMA) with Bill Gates about Covid19

A therapeutic could be available well before a vaccine. Ideally this would reduce the number of people who need intensive care including respirators. The Foundation has organized a Therapeutics Accelerator to look at all the most promising ideas and bring all the capabilities of industry into play. So I am hopeful something will come out of this. It could be an anti-viral or antibodies or something else.

One idea that is being explored is using the blood (plasma) from people who are recovered. This may have antibodies to protect people. If it works it would be the fastest way to protect health care workers and patients who have severe disease.

Speaking of blood and plasma, Alex Tabbarok in MR a while ago:

“A simple and medically feasible strategy is available now for treating COVID-19 patients, transfuse blood plasma from recovered patients.” New York, with other states following closely behind, is now trying the idea.

Read the link within the link above for Alex Tabarrok’s original post as well.

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